Sedation & use of tranquilizers on pets while flying
It has been a standard practice of IATA and its constituent carriers to discourage the use of sedatives and tranquilizers in animals to be transported either as cargo or as cabin baggage due to the potential for adverse effects during transport. This view is endorsed by veterinary organizations such as the American Vet Medical Association.
We do not use sedation & tranquilizers
In general, these drugs are administered prior to or during air transport to minimize the potential for undesirable behavior. Most commonly, drugs such as acepromizine which is in the phenothiazine class of drugs or benzodiazopam have been commonly prescribed. It depresses motor activity as well as the sympathetic nervous system. Animals administered this drug often lose their righting ability and their sense of balance as a function of dose. Depending upon the dosage, they can lose the ability to position themselves and are susceptible to injury as well as obstruction of the airway due to abnormal postures. While this drug has a number of legitimate clinical usages and can be helpful in minimizing aggressive behavior as well as facilitating the induction of anesthesia with other agents, its use without frequent or continual observation of the animal can lead to situations where the animal’s life can be threatened.
It is not established, and probably is unlikely, that tricyclic antidepressants or other available psychotherapeutic agents will reliably alleviate the risk of panic attacks and destructive behavior while in transit. While heavy sedation with all of its associated risks might be able to accomplish this, deciding upon the appropriate dosage to maintain the desired effect over a long and perhaps variable transit time in a varying transit environment and with little chance of re-dosing or adequate observation would either put the animal at risk or may not adequately address the potential for undesirable behavior.
IATA therefore continues to endorse recommendations not to sedate or tranquilize pets or other animals in transit specifically for the purposes of potentially preventing panic attacks or destructive behavior during that period of carriage. If sedation or tranquilization is to be done specifically for the journey for valid medical reasons, it needs to be done under the direction of a veterinarian and the administration of drugs – including time and dosage level—be noted on the health certificate. If such medications are to be used, this should be done only in those shipments accompanied by trained individuals appropriately certified/licensed to administer these drugs and when the ability to take emergency actions in the event of adverse events, exists or is possible.
Source: American Veterinary Medical Association